S. 5383 explained · 119th Congress · Pending in Congress
End Gas Station Heroin Act
Cosponsors: 1 (0 D, 1 R) · per Congress.gov, 2026-10-14
Introduced: 2026-08-08
Latest action (2026-08-08): Read twice and referred to the Committee on the Judiciary.
What S. 5383 does, in plain terms
The Congressional Research Service has not published a summary of S. 5383 yet. Its official title: “End Gas Station Heroin Act”.
Constitution Index
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Not graded yet
S. 5383 has not been graded yet. New measures with an official summary are graded daily under the published rubric.
The Framers
“Founders’ Verdict”
Confidence 0.75
Archived SI output (machine-generated)No editorial review recorded. This historical SI verdict was machine-generated by software and predates the review desk; check it against the official bill text.
Synthesis
The bill is constitutional under the Commerce Clause and Necessary and Proper Clause, but must be applied to interstate commerce only and based on objective evidence to avoid overreach into state police powers.
This bill is a constitutional exercise of Congress's enumerated powers. The regulation of controlled substances, including the scheduling of synthetic opioids and expansion of enforcement actions, falls squarely within the commerce power because such substances are articles of interstate commerce and their manufacture, distribution, and sale substantially affect interstate markets. The necessary and proper clause empowers Congress to enact laws that are appropriate and plainly adapted to the execution of its commerce authority, and this bill is a reasonable measure to address the national cris…
This bill exceeds the enumerated powers of Congress under the Constitution. The regulation of substances like MGM-15, MGM-16, and synthetic alkaloids derived from Mitragyna speciosa is not among the powers delegated to the federal government in Article I, Section 8. The Tenth Amendment reserves such police powers to the states. Furthermore, the bill's expansion of enforcement actions against manufacturers and distributors of 'gas station heroin' encroaches upon the liberty of individuals to engage in commerce and contract, which are rights retained by the people under the Ninth Amendment. The …
The proposed legislation touches upon the federal police power over controlled substances, which is not an enumerated power in the Constitution but has been exercised through the Commerce Clause. However, the bill's expansion of enforcement actions against manufacturers and distributors must be carefully confined to interstate commerce and not intrude upon the reserved police powers of the several states. The scheduling of specific substances, particularly with a threshold for mitragynine derivatives, raises concerns about the precision of legislative findings and the potential for arbitrary o…
This bill falls within the enumerated power of Congress to regulate interstate commerce, as established in Gibbons v. Ogden (1824), which held that Congress may regulate all commerce 'which concerns more States than one.' The substances targeted—synthetic opioids and their analogs—are articles of commerce that move across state lines, and their regulation is a proper exercise of the commerce power. Furthermore, the classification of these substances as Schedule I under the Controlled Substances Act is a means 'necessary and proper' to carry into execution Congress's power to regulate interstat…
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What should pass
“VFA SI Solution”
Archived SI output (machine-generated) · No editorial review recorded
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Synthetic Opioid Control and Interstate Enforcement Act of 2025
Generated by VFA SI Solutions
Prevent the spread of emerging synthetic opioids (including MGM-15, MGM-16, 7-hydroxymitragynine, and mitragynine pseudoindoxyl) by placing them under Schedule I control and strengthening enforcement against manufacturers and distributors, thereby reducing public health harms from 'gas station heroin.'
Bipartisan rationale: Honors Democratic priorities by requiring scientific evidence for scheduling, protecting public health with oversight, and preserving state flexibility; honors Republican priorities by including a sunset, reining in federal overreach, using existing funding sources, and focusing enforcement on interstate commerce rather than broad federal mandates.
Article I, Section 8, Clause 3 Article I, Section 8, Clause 18 Amendment X Amendment V
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