H.R. 3029 explained  ·  119th Congress  ·  Pending in Congress

To amend the Research and Development, Competition, and Innovation Act to support nucleic acid screening, and for other purposes.

Create a free account or sign in to follow H.R. 3029 and get alerts. Policy area: Science, Technology, Communications Create a free account or sign in to follow the Science, Technology, Communications policy area and get alerts. ▲ 91 days since action Sponsor: Andrea Salinas, OR-06, D → Congress.gov

Cosponsors: 3 (2 D, 1 R) · per Congress.gov, 2026-10-15

Introduced: 2025-04-28

Latest action (2026-07-21): Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation.

What H.R. 3029 does, in plain terms

Nucleic Acid Standards for Biosecurity Act This bill explicitly requires the National Institute of Standards and Technology (NIST) to support the development of best practices and technical standards for nucleic acid synthesis. Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), carry genetic information within cells. Nucleic acid synthesis is the process of designing and creating custom nucleic acids; it is used in the development of medications and agricultural products. However, this technology also poses a risk of misuse (e.g., the intentional or unintentional creation of dangerous biological agents). The bill requires NIST to carry out measurement research to support the development and improvement of biosecurity best practices and technical standards related to nucleic acid synthesis. This effort must address specified topics including nucleic acid synthesis screening, operational security, and conformity assessment. (A 2023 executive order titled Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence directed NIST to develop and refine similar specifications and best practices for use by synthetic nucleic acid providers. NIST's work on this topic is ongoing.) In carrying out this effort, NIST must convene stakeholders to develop and periodically update consensus priorities and best practices for synthetic nucleic acid screening mechanisms. Within a specified period, NIST must submit a summary of the stakeholder group’s findings to Congress. NIST must also take steps to advance risk management best practices and technical standards for engineering biology and biomanufacturing, including with respect to risks associated with the use of artificial intelligence.

Official summary by the Congressional Research Service, via Congress.gov.

Constitution Index

“VFA Constitution grade”

B

Minor constitutional concerns

Graded 2026-10-11

SI-generated grade · five published checks · not individually reviewed by a person · methodology

The bill directs the National Institute of Standards and Technology (NIST) to develop voluntary best practices and technical standards for nucleic acid synthesis screening, a function that falls within the federal government's enumerated powers over interstate commerce and national security. It does not mandate compliance, impose penalties, or restrict private conduct, so it does not infringe on individual rights. The main constitutional concern is that the bill consolidates biosecurity standard-setting at the federal level, potentially displacing state and private initiatives, but the voluntary and research-oriented nature of the bill keeps this tension minor.

  • ✓ Passes · Enumerated powers
    The bill authorizes NIST to conduct measurement research and develop voluntary standards for nucleic acid synthesis. This falls within Congress's power to regulate interstate commerce (Article I, Section 8, Clause 3) and to provide for the common defense (Article I, Section 8, Clause 1), as nucleic acid synthesis is used in products that cross state lines and poses biosecurity risks. The action is…
  • ✓ Passes · Bill of Rights
    The bill imposes no restrictions on speech, religion, assembly, press, petition, arms, quartering, search and seizure, self-incrimination, due process, trial by jury, or cruel and unusual punishment. It does not criminalize any conduct or authorize surveillance. The First Amendment is not implicated because the bill does not regulate speech or association; it merely directs NIST to develop volunta…
  • ✓ Passes · Individual sovereignty
    The bill does not restrict what individuals or private entities can do with their own property, labor, or beliefs. It does not mandate compliance with any standard, impose penalties, or require disclosure of private information. The burden of government justification is met because the bill addresses a legitimate national security concern—preventing the misuse of synthetic nucleic acids—without co…
  • ✗ Concern · Decentralization
    The bill fails the decentralization test because it consolidates biosecurity standard-setting at the federal level. While individuals and local communities cannot effectively address global biosecurity risks, states could potentially develop their own standards or coordinate through interstate compacts. However, the bill's voluntary and research-oriented nature, and the need for uniform national s…
  • ✓ Passes · Due process and takings
    The bill does not deprive any person of life, liberty, or property without due process of law. It does not take private property for public use without just compensation. The bill only directs NIST to conduct research and convene stakeholders; it does not impose any binding obligations on individuals or entities.

Sources: Congress.gov: HR 3029 summary

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The Framers

“Founders’ Verdict”

CONSTITUTIONAL

Confidence 0.75

Archived SI output (machine-generated)

No editorial review recorded. This historical SI verdict was machine-generated by software and predates the review desk; check it against the official bill text.

Synthesis

The bill is constitutional as it falls within Congress's enumerated powers under the Commerce Clause (Article I, Section 8, Clause 3), the Patent and Copyright Clause (Article I, Section 8, Clause 8), the Weights and Measures Clause (Article I, Section 8, Clause 5), and the Necessary and Proper Clause (Article I, Section 8, Clause 18). The development of technical standards for nucleic acid synthesis by NIST is a legitimate means to promote scientific progress, regulate interstate commerce, and secure public welfare, without violating the Tenth Amendment.

Hamilton YES

This bill is a constitutional exercise of Congress's enumerated powers. The Commerce Clause (Article I, Section 8, Clause 3) grants Congress the authority to regulate interstate and international commerce. Nucleic acid synthesis is a commercial activity that often involves materials and products crossing state lines, and the development of uniform technical standards for biosecurity directly facilitates the smooth flow of such commerce while preventing harmful disruptions. Furthermore, the Patent and Copyright Clause (Article I, Section 8, Clause 8) empowers Congress to promote the progress of…

Article I, Section 8, Clause 3 Article I, Section 8, Clause 8 Article I, Section 8, Clause 18 Federalist No. 23
Jefferson NO

The Constitution enumerates only limited powers to the federal government. Nowhere does it authorize Congress to establish technical standards for nucleic acid synthesis or to direct the National Institute of Standards and Technology to engage in such activities. The promotion of science and the setting of standards for biosecurity are not among the enumerated powers in Article I, Section 8. The Tenth Amendment reserves all powers not delegated to the United States to the states or the people. While the Commerce Clause grants Congress authority over interstate commerce, the mere possibility th…

Amendment X Article I, Section 8
Madison YES

The bill authorizes the National Institute of Standards and Technology to develop technical standards and best practices for nucleic acid synthesis, a power that falls within the constitutional authority of Congress to fix the standard of weights and measures. This enumerated power, found in Article I, Section 8, Clause 5, has been understood to extend to a wide range of measurement standards necessary for commerce and public safety. Moreover, the regulation of synthetic nucleic acids implicates interstate commerce and the general welfare, as the misuse of such technology could pose dangers to…

Article I, Section 8, Clause 5 Article I, Section 8, Clause 18 Federalist No. 10 Federalist No. 45
Marshall YES

This bill is constitutional as it falls within the enumerated powers of Congress to promote the progress of science and useful arts, and to regulate interstate commerce. The establishment of standards for nucleic acid synthesis is a necessary and proper means to secure the public welfare and prevent the misuse of technology that could affect interstate and foreign commerce. The Constitution vests Congress with the power to 'promote the Progress of Science and useful Arts' (Article I, Section 8, Clause 8) and to 'regulate Commerce with foreign Nations, and among the several States' (Article I, …

Article I, Section 8, Clause 3 (Commerce Clause) Article I, Section 8, Clause 8 (Copyright and Patent Clause) McCulloch v. Maryland (1819)
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